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乳腺癌bcl-2、bax基因的表达及其临床意义 被引量:2

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摘要 应用免疫组化检测86例乳腺导管浸润癌bcl-2和bax的表达,并进行统计学分析。结果bcl-2在不同分级的癌组织中表达分别是Ⅰ级77.78%,Ⅱ级53.85%,Ⅲ级30.30%(P<0.05);在淋巴结阳性组和阴性组中的表达分别是39.21%和71.43%(P<0.05)。bax在不同分级癌组织中的表达分别是Ⅰ级33.33%,Ⅱ级57.69%,Ⅲ级84.88%(P<0.05);在淋巴结阳性组和阴性组的表达分别是70.59%和42.86%(P<0.05)。认为bcl-2和bax表达与乳腺癌组织学分级和淋巴结转移有关。
机构地区 滨州医学院
出处 《山东医药》 CAS 北大核心 2006年第31期42-43,共2页 Shandong Medical Journal
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