毛细管气相色谱法测定冰片中有机溶剂残留量

Determination of Risidual Solvents in Bornrolum Syntheticum by Capillary Gas Chromatography

本文建立了毛细管气相色谱法同时检测冰片中“三苯”残留量。无水乙醇作为溶剂直接进样分析。在0．88～8．8μg／ml范围内，峰面积与三苯浓度之间呈良好的线性关系（R〉0．9995）。平均加标回收率分别为98％（苯）、103％（甲苯）、102％（对-二甲苯或间-二甲苯）、102％（邻-二甲苯）。检出限分别小于0．8μg/kg（苯）、0．88μg,／kg（甲苯）、0．87μg,／kg（对-二甲苯或间-二甲苯）、0．87μg／kg（邻-二甲苯）。精密度（RSD）均小于5％。

A menthod for determination of three solvents in Bornrolum Syntheticum has been established, The residual solvents of benzene ,tolune and xylene（ m ,o ,p） were quantatively determined by capillary GC using ethanol absolute as the solvent. Three residual solvents were completely separatetd. The linearity ranges were 0.88 - 26μg （r： 〉 0.9995 ）and the detection limits of benzene ,tolune and xylene（ m ,o ,p） were 0,88μg/kg,0.88μg/kg,2.64μg/kg respectively. The average recovery rates were in the range of 98%- 103%. The relatve standard deviations （RSD）were less then 5%.