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由发酵液提取泰乐菌素C的初步研究 被引量:1

Preliminary Study on Extraction of Tylosin C from Fermentation Broth
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摘要 研究了从发酵液中提取泰乐菌素C的工艺条件,确定了甲苯为萃取溶剂,在pH9.25~10.02萃取3次,继而用乙酸乙酯在pH9.44条件下进一步萃取,30%酒石酸溶液反萃取至水相(pH3.88),得到纯度84%的酒石酸泰乐菌素C溶液。 A process for the extraction of tylosin C from fermentation broth was investigated and optimized. The filtrate was firstly extracted for three times using toluene at pH 9.25 - 10.02, and then the extracts were further extracted with ethyl acetate at pH 9.44. Tylosin C with the purity of 84 % was extracted again from ethyl acetate phase to water phase at pH 3.88 by 30% tartaric acid.
出处 《中国医药工业杂志》 CAS CSCD 北大核心 2006年第11期731-733,共3页 Chinese Journal of Pharmaceuticals
关键词 泰乐菌素C 提取 发酵液 tylosin C extraction fermentation broth
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