摘要
综述了抗抑郁药物的作用机制(单胺递质理论、神经递质受体理论、受体后神经细胞信号转导理论)、药物分类(三环类、单胺氧化酶抑制剂、可逆性单胺氧化酶抑制剂、选择性5-HT再摄取抑制剂、选择性NA再摄取抑制剂、5-HT和NA双重再摄取抑制剂、NA能和特异性5-HT能抗抑郁药等)及研究现状。
The outline of antidepressants is reviewed, including the mechanism of action, the classification and the progress. The mechanism is related to monoamine transmitter hypothesis, neurotransmitter receptor hypothesis and post-receptor signal transduction hypothesis. The antidepressants are classified into TCAs, MAOIs, RIMAs, SSRIs, NaRis, SNRis and NaSSAs.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2006年第11期779-783,共5页
Chinese Journal of Pharmaceuticals
关键词
抗抑郁药
作用机制
分类
综述
antidepressants
mechanism of action
classification
review
