胰腺癌骨转移

Bone metastases of pancreatic cancer

目的探讨胰腺癌骨转移的诊断与治疗。方法回顾性分析1999年至2003年间胰腺癌骨转移病例2例。结果经X线、B超、CT、ECT,淋巴细胞rDNA分析,肿瘤细胞学检查、肿瘤标记物检测等方法确诊。1例女性胰腺低分化腺癌,术后2年胸椎及右骶髂骨转移,接受放疗后半年后死亡;1例男性胰腺癌伴胸腰椎骨转移,在行梗阻性黄疸内引流术后1个月因肺部感染,呼吸衰竭死亡,尚未能接受对骨转移灶的治疗。结论影像学检查是发现骨转移瘤的主要方法。胰腺癌骨转移,预后差,除对原发肿瘤治疗外,应积极治疗骨转移灶以延长此类晚期患者的生存期及提高生活质量。

Objective To study the diagnosis and treatment of bone metastases of pancreatic cancer. Methods To retrospective analyses 2 cases of the bone metastases of pancreatic cancer. Results To diagnoses bone metastases of pancreatic cancer with by X-ray, ultrasound, CT, ECT, DNA analyses of lymphocyte, tumor cytological examination, tumor marker and so on. One female case with poor differentiated adenocarcinolna of pancreas was diagnosed bone metastases after 2 years of her initial pancreatic duodenectomy. She took the treatment of the radiotherapy and was dead after 6 months. Another case with pancreatic cancer has bone metastases and received the biliary-enterostomy, he was dead because of the lung infection and respiratory failure after 1 month of the operation. Conclusions The examination of the image is the main measure to find the bone metastases. It is poor prognosis in the patients of pancreatic cancer with bone metastases. In allusion to the pancreatic cancer with bone metastases beside treatment of the primary affection, at the same time to treatment the bone metastases in order to improve the survival rate and the life quality of the cases.