乌体林斯对哮喘患儿T淋巴细胞亚群的影响

Affection of Wutilinsi for T Lymphoctye Subpopulation of Children with Asthma

目的:研究乌体林斯对哮喘患儿T淋巴细胞亚群的影响。方法:采用自身对照试验,对38例哮喘患儿肌注乌体林斯治疗8周,治疗前后分别抽血查T淋巴细胞亚群及IgE抗体。结果:治疗后CD4显著降低(P<0.01);CD8显著升高(P<0.01);CD4/CD8比值显著降低(P<0.01);IgE显著降低(P<0.001),治疗效果38例中显效27例(71.05%),有效8例(21.05%)。结论:乌体林斯能够明显改善支气管哮喘患儿的免疫功能,值得推广。

Objective： To study affection of Wutilinsi for T lymphoctye subpopulation of Children suffering asthma. Methods： 38 children suffering asthma were treated with Wutilinsi for 8 weeks by Auto--control test, and blood level of T lymphoctye subpopulation and IgE antibody were detected before and after treatment. Results： After treatment, level of CD4 was obviously decreased （P^0.01）~ level of CD8 was significantly increased （P〈0.01）. Ratio of CD4/CD8 was also decreased （P〈0.01） ; level of IgE was decreased （P〈O. 001）. The results showed that 27 samples among 38 patients were significantly effective （71.05%） and 8 samples among 38 patients were effective （21.05%）. Conclusions： Wutilinsi can improve immunologic function of the children suffering bronchial asthma.