限制性液体复苏治疗失血性休克的应用研究

The study of the therapeutic effect of limited fluid resuscitation on trauma and hemorrhagic shock

目的 探讨液体复苏对创伤失血性休克的救治效果。方法 回顾性总结创伤失血性休克早期不同的液体复苏方法对救治效果和凝血功能的影响。结果 在243例创伤失血性休克患者中，充分液体复苏组（127例）病死率37．80％（48例），限制液体复苏组（116例）病死率23．28％（27例），两组总病死率及1～2h病死率比较差异均具有统计学意义（P＜0．05）。充分液体复苏组血浆凝血酶原时间（PT）长于和存活患者并发症的发生率高于限制性液体复苏组。结论 限制性液体复苏能降低创伤失血性休克患者病死率，提高存活率，并降低存活患者并发症的发生率，改善预后。

Objective To investigate the therapeutic effect of fluid resuscitation on hemorrhagic shock. Method Different kinds of fluid resuscitation were used to treat patients with hemorrhagic traumatic shock. The treatment effect and coagulation function were retrospectively analyzed. Results In adequate fluid resuscitation group, both the total mortality and the first-two-hour mortality were significantly higher than those of limited group （P 〈 0.05 ）. Furthermore, the prothrombin time （PT） was longer and the complication rate of survival patients in adequate group was higher than those in the limited group. Conclusion Limited fluid resuscitation could reduce the mortality of severe hemorrhagic traumatic shock, improve the survival rate, and reduce complications in survival patients.