摘要
目的建立盐酸金刚烷胺片的含量测定方法。方法采用紫外-可见分光光度法测定,测定波长为(412±1)nm。结果盐酸金刚烷胺浓度在2．5-15μg／mL范围内与吸收度呈良好的线性关系(r=0．999 5,n=6),平均回收率为99．88％,RSD=0．69％(n=6)。结论紫外-可见分光光度法灵敏,准确可靠,重现性好,可用于盐酸金刚烷胺片的含量测定。
Objective To establish a method for determining the content of amantadine hydrahloride tablets by ultraviolet visible spectrophotometry. Methods The content of amantadine hydrahloride tablets was determined by ultraviolet visible spectrophotometry, the wavelength was at （412 ±1）nm. Results Amantadine hydrahloride tablets presented a good liner relationship within a range of 2.5- 15 μg/mL, r =0. 999 5 （n =6）, the average recovery rate of amantadine hydrahloride was 99.88%, RSD was 0. 69% （n =6）. Conclusion The ultraviolet visible spectrophotometry is sensitive, accurate, reliable and repeatability, and can be used as a method of＇ quality control of amantadine hydrahloride tablets.
出处
《中国药业》
CAS
2006年第15期44-45,共2页
China Pharmaceuticals
