黑刺菝葜茎的化学成分研究

Study on Chemical Constituents from Stem of Smilax scobinicaulis

目的研究黑刺菝葜茎的化学成分，为充分利用黑剌菝葜药用植物资源鉴定基础。方法利用大孔树脂、硅胶和sephadex LH-20等色谱分离手段进行分离纯化，通过理化性质和光谱分析鉴定结构，结果从黑刺菝葜茎乙醇提取物的乙酸乙酯、正丁醇萃取物分离鉴定了5个化合物，分别为反式白藜芦醇（1）、槲皮素-3-O-β-D-葡萄糖苷（2）、木犀草素-7-O-β-D-葡萄糖苷（3）、拉克索皂苷元-3-O-[α-L-吡喃阿拉伯糖基-（1→6）]-β-D-吡喃葡萄糖苷（4）、拉克索皂苷元-3-O-[β-D-吡喃葡萄糖基-（1→4）][α-L-吡喃阿拉伯糖篡．（1→6）]-β-D-吡喃葡萄糖苷（5）。结论化合物1—3首次从本植物中分离得到。

OBJECTIVE To isolate and elucidate the chemical constituents from the stem of Smilax scobinicaulis C. H. Wright. METHODS Column chromatography csilica gel, macroporous resin, and sephadex LH - 20 were used to isolate the constituents. Their structures were elucidated by physical and spectral data. RESULT Five compounds are isolated and their structures were identified as trans-resveratrol （ 1 ）, quercetin-3- O-β-D-glucopyranoside（2）, luteolin-7- O-β-D-glucopyranoside （3）, laxogenin-3- O- [ α-L-arabinopyranosy 1- （1→6） ]-β-D- glucopyranoside （4）, laogenin-3-O- [ β-D-glucopyrnosyl- （ 1→4）- 0- [ α-L-arabinopyranosyl- （1→6） ]-β-D-glucopyranoside（5）. CONCLUSION Compound 1 - 3 are isolated from this plant for the first time.