摘要
目的分析和总结1998年-2005年8年间，福建南部三地市（厦门、漳州和龙岩）新生儿先天性甲状腺功能低下症的筛查状况。方法新生儿出生后72h采足跟血，滴在规定的滤纸上，采用时间分辨荧光免疫测量法（DELFIA法）测定TSH浓度。结果福建南部三地市1998～2005年，共筛查251833例新生儿，确诊先天性甲状腺功能低下症患儿149名，发病率1／1690。结论福建南部具有较高的先天性甲状腺功能低下症发病率，开展对该疾病的筛查和治疗具有重要意义。
Objective： To analyse the situation of neonatal screening for congenital hypothyroidism （CHT） in south area of Fujian Pro. from 1998 to 2005. Methods： Sample of heel blood collected from newborn after 72 hours, and dropped on stipulated filter paper to determine the TSH concentration of blood according to DELFIA. Results： From 1998 to 2005, 251833 newborn babies have been surveyed, and 149 babies have been confirmed as CHT patients, the incidence rate was 1/1690. Conclusion： There are high CHT inci- dence rate in south area of Fujian Province. It was great significance to screen and treat this disease.
出处
《中国优生与遗传杂志》
2006年第11期89-90,91,共3页
Chinese Journal of Birth Health & Heredity
