低剂量X线照射垂体区治疗老年良性前列腺增生症临床研究

Low-dose X-ray radiation on pituitary gland area to treat benign prostatic hyperplasia

目的 探讨低剂量X线照射垂体区治疗老年良性前列腺增生症（BPH）的临床疗效。方法 用6mV X射线外照射BPH患者脑垂体区，每次1．2Gy，每周2次，总剂量4．8～6．0Gy；测定治疗前后尿流率和残余尿量的变化。结果 近期有效率78％，1年有效率70％，照射后尿流率明显增加（P〈0．05）。结论 该疗法无创伤，简便、安全，是年老多病不能手术治疗或药物治疗无效的BPH患者的首选治疗方法。

Objective To investigate the effects of low-doseX-ray radiation on pituitary gland area to treat benign prostatic hyperplasia. Methods Using the linear-accelerator 6mV X-ray to radiation on pituitary gland area, 1.2Gy/f,2 times/week, total dose was 4.8- 6.0Gy, The uro-flow rate and residual urine volume were measured. Results The immediate effect was 77.5 %,the 1-year effect rate was 70 %. After treatment,the uro-flow rate was significantly increased（ P 〈 0.05）. Conclusion The method has no damage, no pain and no side effect. It is simple, convenient and safe,and the effect is good. It is the first selective method for old and sick patients of BPH.