甲硝唑复合剂治疗急性根尖周脓肿的疗效观察

Clinical effect of Flagyl compound on acute periapical abscess

目的观察甲硝唑复合剂治疗急性根尖周脓肿的疗效。方法选择186例患急性根尖周脓肿的恒牙及乳磨牙患者，随机分为药物组（甲硝唑复合剂）93例，对照组（常规根充糊剂）93例，做常规根管预备后进行根管充填。术后1～3年复查，对疗效进行评价。结果药物组治疗后症状消除迅速，1年有效率为31．18％，2年为34．4％，3年为30．10％，总有效率为95．69％，2年以上远期治疗有效率明显；对照组1年为33．33％，2年为30．0g％，3年为24．72％，总有效率为88．14％。药物组治疗有效率高于对照组。结论甲硝唑复合剂是治疗急性根尖周脓肿理想的充填材料，尤其是对未形成瘘者及乳磨牙急性根尖周脓肿者效果最佳。

Objective To observe the therapeutic effect of Flagyl compound on acute periapical abscess. Methods Permanent or deciduous teeth in 186 patients with acute periapical abscess were selected in this study. They were divided at random into drug group （Flagyl compound, n = 93） and control group （routine cataplasm filling, n = 93）, in which, the root canals were filled after routine preparation. The effects were evaluated after 1-3 year follow-up. Results The symptom in drug group disappeared rapidly after treatment. The effective rates were respectively 31.18%, 34. 40% and 30. 10% in 1 year, 2 years and 3 years, with the total effective rate of 95.68%. The long-term curative effect was apparent. In control group, they were respectively 33.33%, 30.09%and 24.72%, with 88.14% of total effectiveness. The effective rate was superior in drug group to control group. Conclusion As a root canal filling materials, Flagyl compound has a remarkable long-term effect with minor poisonousness and side effects on acute periapical abscess in permanent and deciduous molars, especially when the periapical abscess is not apparent and the fistulae has not formed.