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精索静脉曲张不育患者免疫学和性激素的研究 被引量:11

The study of immunology and sex hormone level changes in varicocele-induced infertility
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摘要 目的:了解精索静脉曲张(VC)患者的免疫功能和性激素状态,为所致不育提供参考资料。方法:选择20例24~35岁VC患者精索静脉血和外周静脉血进行免疫细胞、性激素和精液检测。随机选择18例年龄相同、已生育的腹股沟斜疝患者为对照组。同法检测。结果:VC患者多项免疫指标值低于对照组,精索静脉血性激素与对照组差异有显著性。结论:VC患者机体免疫功能降低。可能是破坏血睾屏障、损害睾丸致睾酮降低的原因之一;精索静脉血可反映VC患者血中性激素实际水平。 Objective:To understand the immune function and sex hormone serum levels of the male with varicocele (VC) and provide reference data for the male infertility. Methods:After the spermatic and peripheral vein blood were taken from 20 cases (aged from 24~35years) with VC,immune cells and sex hormone and sperm was detected, while 18 cases married and born cases with the inguinal hernia and the same age were selected at random the countrol group. Results :The immune values of the male with VC were lower than that of the control group ,the sex hormone in spermatic venous blood had significant statistic difference. Conclusion:The immune function of the male with VC is reduced,which may be one of the reasons that destroyed the blood testis barrier and damaged testis function and reduced testosterone. The concentration of serum sex hormone in spermatic venous blood might reflect the truth better.
出处 《临床医药实践》 2006年第11期808-810,共3页 Proceeding of Clinical Medicine
关键词 精索静脉曲张 男性不育 免疫 性激素 精索静脉血 varicocele male infertility immune sex hormone spermatic vein blood
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