血清胆红素水平在冠心病诊断中的意义

Serum bilirubin concentration in diagnosis of coronary heart disease

目的:探讨血清胆红素水平变化对冠心病(coronary heart disease,CHD)诊断的意义。方法:设冠心病组(CHD组)52例与对照组36例,测定血清总胆红素(TBIL)、总胆固醇(CHO)、甘油三酯(TG)、高密度脂蛋白(HDL)。结果:CHD组TBIL浓度明显低于对照组(P<0.01),CHD组TBIL浓度与CHO、TG均呈负相关关系(P<0.01),与HDL呈正相关关系(P<0.01)。结论:TBIL具有防止脂质氧化,从而可减少CHD的发生。

Objective ：To explore the value of serum bilirubin level in diagnosis of coronary heart disease（CHD）. Methods：Fifty-two patients with CHD and thlrty-six normal controls were divided into two groups. Total bilirubln （TBIL） in serum, total cholesterol （CHO）, triglyceride （TG） and high-density lipoproteins （HDL） were measured. Results：The TBIL in serum in patients with CHD was lower than that in normal controls （ P 〈 0.01 ）. The TBTL in CHD group showed negative correlativity with CHO and TG （ P 〈 0.01 ）. The TBTL in CHD group showed positive correlativity with HDL（ P 〈 0.01 ）. Conclusions： TBIL in serum could prevent lipid from oxidation and reduce the occurrence of CHD.