药物联合治疗真菌性角膜炎20例分析

Combined drug therapy of 20 patients with fungal keratitis

目的:探讨斯皮仁诺、那他霉素滴眼液、抗生素联合应用治疗真菌性角膜炎的效果,并与单纯使用抗真菌药物比较。方法:8例轻度角膜炎单服斯皮仁诺。12例中、重度角膜炎使用斯皮仁诺、那他霉素滴眼液、抗生素联合治疗。结果:20例真菌性角膜炎全部治愈,2例并发角膜溃疡穿孔行结膜瓣移植,均保住眼球。结论:斯皮仁诺、那他霉素滴眼液、抗生素联合用药对真菌性角膜炎治疗效果好。

Objective：To investigate the effect of sporanox, natamycin eye drops and antibiotics on mycotic keratitis. Methods：Eight patients with mild keratitis were treated only with sporanox. Twelve patients with middle, severe keratitis were treated with sporanox, natamycin eye drops, and antibiotics in combination. Results：Twenty patients with mycotic keratitis were all cured. Two patients with corneal ulcer and perforation were transplanted with conjunctival flap, the eyeball were all protected. Conclusions：The theraputic effects of combination of sporanox,natamycin eye drops, and antibiotics are of efficacy on mycotic keratitis.