41例老年人肾病病理与临床分析

Clinicopathologic Analysis of Renal Disease in 41 Elderly Patients

分析４１例老年人肾病肾活检的病理与临床特征。结果显示４１例中３８例为肾小球疾病。老年人肾小球疾病的病理分布：原发性者以局灶节段性硬化最多见；继发性者以糖尿病肾病和肾淀粉样变最常见。肾病综合征是老年肾小球疾病的常见临床表现，其病理分布：原发性者以膜性肾病最多见；继发性者以肾淀粉样变和糖尿病肾病为主。此外，结合肾病理改变对老年人肾病临床特征作了分析。

The clinical and pathologic feature were investigated in 41 elderly patients (aged>60 years) with renal disease provided from 1187 renal biopsies. The renal histological changes showed: 38 patients with glomerulopathy, 30 cases were primary glomerulopathy (78.9%). Among these FSGS was the most common histological type(40.0%). 8 secondary cases the most common type were diabetic and amyloid nephropathy. The clinical features showed: NS was the most common manifestation of glomerulopathy in the elderly. In our data, MN was the most common histological type of primary NS; the diabetic and amyloid form were the most common of secondary NS. The relationship between pathologic type and clinical manifestation of glomerulopathy in the elderly were analyzed.