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白细胞介素-18与全身型幼年特发性关节炎的关系 被引量:1

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摘要 全身型幼年特发性关节炎(sJIA)是小儿风湿病中较常见的类型之一。以弛张热为主要表现,临床缺乏较特异的实验室诊断指标;白细胞介素-18(IL-18)是干扰素-γ(IFN-γ)诱导因子,在sJIA的发病中起重要作用,对其诊断及病情判断具有重要价值。本文拟结合国内外最新报道对IL-18的生物学特点及活性I、L-18基因多态性与Still′s病的关系I、L-18在sJIA中的重要作用、IL-18的免疫治疗前景作一综述。
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2006年第21期1509-1511,共3页 Journal of Applied Clinical Pediatrics
基金 上海市科委基金项目资助(044119716)
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