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癌患者的NK细胞和LAK细胞活性及MPS治疗对其的影响

NK and LAK Cell Activity of Cancer Patients and Effects of MPS on It
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摘要 观察了47例癌患者和13例健康人的NK细胞、内源性LAK细胞对靶细胞的杀伤活性及NK细胞计数。结果表明,癌患者该3项指标均显著低于对照组(P<0.001),尤以晚期癌症和发生远处转移患者的降低为著。不同种类的癌和有无淋巴结转移的患者之间该3项指标无显著性差异。使用MPS免疫治疗2周,可显著提高患者的上述3项指标(P<0.001、P<0.001、P<0.05)。 The NK and endogenous LAK activity and the numbers of NK cell were observed in 47 cancer patients and in 13 healthy volunteers. The results revealed that the levels of the three indications were significantly lower in the patients than in the normal controled group(P<0. 001) and the decline were conspicuous in the patients with late stage cancer and distant metastases. Treatment by mycobacterial polysaccharides (MPS) for two weeks has enhanced the levels of these indications in the patients after operation.
出处 《首都医科大学学报》 CAS 1996年第3期193-196,共4页 Journal of Capital Medical University
关键词 NK细胞 LAK细胞 分枝杆菌多糖 肿瘤 cancer NK cell LAK cell mycobacterial polysaccharides
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  • 1王长安,许荣,李中华.天然细胞毒测定-LDH释放法[J]中国免疫学杂志,1988(01).

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