摘要
目的:研究舒脑胶囊的质量控制方法。方法:采用薄层色谱法鉴别舒脑胶囊中三七、牛膝及泽泻;以苯酚硫酸分光光度法在490nm波长处测定本品中总多糖含量。结果:薄层色谱中能明显检出三七、牛膝及泽泻;测得总多耱含量为0.626%~0.667%;总多糖在5.6~11.2mg·L^-1范围内呈良好线性关系,r=0.9999.平均回收率为98.61%(n=6).RSD为2.38%。结论:质量控制方法简单、可靠.能有效控制该制剂的内在质量。
OBJECTIVE To study the quality control of shu'nao capsules. METHODS Radix Notoginsengg,Radix Achyranthis Bidentatae and Rhizoma Alis,zatis in this product were indentified by TLC, the total Polysaccharides of shu'nao capsules was determined by phenobsulphuric acid spectrophotometry. RESULTS Radix Notoginseng ,Radix Achyranthis Bidentatae and Rhizoma Alismatis could be obviously identified by TLC. The content of the total polysaccharides in this capsules was 0. 626 - 0. 667%. The linear relationship were good in the ranges of 5.6- 11.2 mg· L^-1. The average recovery was 98. 62%, RSD= 2.38%(n = 6). CONCLUSION This quality control method is simple,accurate and can be used to control the quality of shu ' nao capsules.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2006年第11期1335-1338,共4页
Chinese Journal of Hospital Pharmacy
基金
甘肃省2003年度中医药管理局项目(编号:2003-GZK-24)
关键词
舒脑胶囊
质量控制
苯酚-硫酸分光光度法
薄层色谱法
多糖
Shunao capsules
quality control
phenol-sulphuric acid
spectrophotometry: TLC
polysaccharides