摘要
高效液相色谱-质谱联用技术具有高分离能力、高灵敏度、应用范围广和极强的专属性等特点。对高效液相色谱-质谱联用技术在药物分析、食品分析和环境分析等领域的应用,特别是在中草药成分分析、中药指纹图谱研究、药物代谢研究、体内药代动力学研究、西药及中成药成分分析、药物筛选研究等方面的应用进行了综述。
High performance liquid chromatography - mass spectrometry （HPLC - MS） is a new technique, which has developed very fast in the recent years. It is regarded as an important technology for many advantages such as high separating efficiency, good sensitivity, wide application and strong specific. HPLC - MS has been widely used in various fields such as pharmaceutical, food and environmental area. Its applications and the latest progresses especially in pharmaceutical analysis aspect including Chinese herb medicine, fingerprint of traditional Chinese medicine, metabolites, pharmacokinetics, western medicine and Chinese traditional patent medicine and drug screening aspects are reviewed in this paper.
出处
《化学分析计量》
CAS
2006年第6期99-103,共5页
Chemical Analysis And Meterage
关键词
高效液相色谱
质谱
联用
综述
high performance liquid chromatography, mass spectrometry, review
