摘要
56例慢性浅表性胃炎患者,随机分成次枸橼酸铋(De-Nol)组和麦滋林-S组,治疗时间8周。结果De-Nol组胃窦炎症程度及活动度改善明显优于麦滋林-S组。重度炎症由42.9%减为10.3%,轻度炎症;由17.0%增至42.9%;100%的炎症转为非活动性;其对幽门螺杆菌的清除率(80%)明显优于麦滋林-S组(41.7%);对胃粘膜血流量的改善也非常明显,由2.33±0.10V增加到3.21±0.10V。这进一步肯定DeNol治疗慢性胃炎具有提高胃粘膜防御因子和削弱攻击因子双重作用。
6 patients with chronic superficial gastritis(CSG)were randomly divided into two groups,and treated with Colloidal Bismuthi Subcitras(CBS,De-Nol) and Mqrzulene-S as controlrespectively.The period of treatment were lasted for 8 weeks.Our results showed that De-Nolgroup has a better role on the treatment of CSG than that of Mqrzulene-S group both in reducingthe inflammatory degree and improving the inflammatory activity of antrum. After treated withDe-Nol,the number of severe inflammations decreased from 42.9%to 10,3%and mileinflammations increased from 17.0%to 42.9%. Also,100%of inflammation became inactive;On the other hand,the effects of De-Nol on HP eliminating rate were also better than Mqrzulene-S(80%vs 41.7%).In the same time.the gastric mucosal blood flow(GMBF) was obviouslyimproved by De~Nol therapy(from 2.33±0.10 to 3.21±0.10V).These results demonstratedthat De-Nol has a double-role on the treatment of chronic gastritis which enhancing the role ofgastric mucosa defense factors and weakening the role of attack factors.
出处
《基础医学与临床》
CSCD
1996年第5期384-387,共4页
Basic and Clinical Medicine
关键词
胶体铋
胃炎
次枸椽酸铋
Colloidal Bismuthi Subcitras(De-Nol)HP Gastric Mucosal Blood Flow(GMBF)Department ofMicrocirculation and Diabetes Mellitus.Department of Pathyology