摘要
犬急性呼吸性酸中毒(ARA)模型通过吸入8%~10%CO_2气体产生。在ARA6h期间,对照组和氨苯蝶啶组PaCO_2、[HCO_3]s和脑脊液(CSF)PCO_2分别升高约5.0kPa、4.0mmol/L和5.8kPa,两组之间比较无显著差异。然而,两组的改变却相差非常显著(p<0.01),对照组平均升高8.5mmol/L,氨苯喋啶组平均升高4.5mmol/L,两组的差不能用CSF其它离子浓度改变所解释。结果表明ARA时,Na ̄+/H ̄+交换可能在调节中有一定作用。
cute respiratory acidosis in dogs were induced by 8%~10%CO_2 breathing during 6hours,During Acute respiratory acidosis in 6 hours, arterial PCO_2,plasma and cere-brospinal fluid (CSF)PCO_2 rose respectively by about 5.0kPa,4. 0mmol/L and 5.8kPa in bothgroups (p>0.05).However,changes in CSF were significantly different between the twogroups(p<0.01);in the control group,mean rose by 8.5mmol/L in 6 hours afterinduction of acute respiratory acidosis. In the triamterene group,the rise was only 4.5mmol/LThe differences in could not be ascribed to differences in CSF other ion concertra-tion, We conclude that Na+-H+ exchange may play a role in the regulation of dur-ing acute respiratory acidosis in dogs.
出处
《基础医学与临床》
CSCD
1996年第4期301-304,共4页
Basic and Clinical Medicine
关键词
脑脊液
酸碱调节
呼吸性
酸中毒
脑脊液
Cerebrospinal fluid Acid-base regulation Triamterene Respiratory acidosis