复方醋酸氯己定消毒剂杀菌效果试验观察

EXPERIMENTAL OBSERVATION ON GERMICIDAL EFFICACY OF COMPOUND CHLORHEXIDINE ACETATE DISINFECTANT

为了解复方醋酸氯己定消毒剂的杀菌效果,用悬液定量杀菌试验和现场试验进行了试验观察.结果,以含醋酸氯己定1540 mg/L的该复方消毒剂原液对金黄色葡萄球菌、大肠杆菌作用3 min,杀灭对数值均＞5.0.用该消毒剂对手与前臂皮肤作喷雾湿润消毒2～3 min,可对自然菌平均杀灭对数值均＞1.0.用该消毒剂原液对45 m3的房间按8 ml/m3用量进行气溶胶喷雾消毒作用30 min,对空气中自然菌的平均消亡率为97.5%.将该消毒剂原液密封储存于37℃ 90 d,醋酸氯己定含量下降率为1.94%.结论,该消毒剂性能稳定,对细菌繁殖体和皮肤自然菌杀灭效果较好.

In order to know the germicidal efficacy of compound chlorhexidine acetate disinfectant, suspension quantitative germicidal test and field trial were used to carry out experimental observation. Results： The killing logarithm values of Staphylococcus aureus and Escherichia coli exposed to the stock solution of the compound disinfectant containing chlorhexidine acetate 1540 mg/L for 3 min were 〉 5.0. Spraying moistening disinfection of hands and forearms with the disinfectant for 2 ～3 min could kill the natural bacteria by a logarithm 〉 1.0 in average. Aerosol spraying disinfection of a 45 m^3 room with the stock solution of the disinfectant at a dosage of 8 ml/m^3 for 30 min caused 97.5% eradicating rate of natural bacteria in air. After the stock solution of the disinfectant was stored in sealed contition at 37℃ for 90 days, its chlorhexidine acetate content decreased by 1.94%. Conclusion ： The disinfectant is stable and has good efficacy in killing vegetative forms of bacteria and natural bacteria on skin.