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IκB激酶-β与慢性肝病

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摘要 IκB激酶-β(IKK-β)是核因子-κB活化所必需的催化亚单位,在受到脂多糖、炎症细胞因子等刺激时呈高表达,通过调节炎症相关基因和抗凋亡基因的表达在慢性肝病的发生发展中起重要作用,应用IKK-β特异抑制剂可能有助于减轻相应的肝脏病变。
出处 《国外医学(内科学分册)》 2006年第11期464-467,共4页 Foreign Medical Sciences(Section of Internal Medicine)
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