脊髓纵裂神经缺陷机制探讨

A STUDY ON MECHANISM OF NEURAL DEFICIT IN DIASTEMATOMYELIA

对２９例脊髓纵裂的神经功能状态进行临床评价及胫后神经皮层体感诱发电位（ｐｏｓｔｅｒｉｏｒｔｉｂｉａｌｎｅｒｖｅｃｏｒｔｉｃａｌｓｏｍａｔｏｓｅｎｓｏｒｙｅｖｏｋｅｄｐｏｔｅｎｔｉａｌ，ＰＴＮＣＳＥＰ）检查。结果：患病组２９例两下肢间神经缺陷的临床评分及ＰＴＮＣＳＥＰ有显著差异（Ｐ＜０．０５），患病组５８根ＰＴＮＣＳＥＰ明显异常；手术组２０例术后神经缺陷的临床评分及ＰＴＮＣＳＥＰ异常明显改善（Ｐ＜０．０５），非手术组９例随访后则无改善（Ｐ＞０．０５）。结果提示神经缺陷的机理是脊髓纵裂间隔对脊髓的牵拉和纵裂脊髓单侧发育异常。

patients with diastematomyelia(operation group of 20 patients,conservation group of 9 patients) were studied by evaluating clinical neural function and measuring posterior tibial nerve cortical somatosensory evoked potentials(PTNCSEP).The results showed that clinical scores and PTNCSEP had significant difference between bilateral lower extremities in 29 patients (P<0.05): Clinical scores and PTNCSEP improved significantly in operation group after the operation(P<0.05),and had not significant improvement in conservation group (P>0.05). These suggest that the mechanism of neural deficit is traction of the septum to the spinal cord and asymmetrical developmental anomalies of the cord.