血清CPK、LDH、GOT和LAP活性对急性颅脑损伤的诊断价值

A STUDY OF SERUM CPK、LDH、GOT AND LAP ACTIVITIES FOR THE DIAGNOSIS OF ACUTE HEAD INJURY

对８０例急性颅脑损伤患者血清ＣＰＫ、ＬＤＨ、ＧＯＴ和ＬＡＰ活性进行了测定。结果显示，急性颅脑损伤后血清ＣＰＫ和ＬＤＨ活性显著升高（Ｐ＜０．０５），而血清ＧＯＴ和ＬＡＰＩ活性升高不明显（Ｐ＞０．０５），至于血清酶活性对判断急性颅脑损伤的脑损伤程度和患者预后的价值有待继续探讨。

The activities of creatine phosphokinase(CPK),lactic dehydrogenase (LDH),glutamic oxaloacetic transaminase(GOT) and Leucine aminopeptidase (LAP) in serum were measured in 80 patients with acute head injury. The results showed that the activities of CPK and LDH in serum were remarkably increased within 24 h after trauma (P<0. 05),but the activities of GOT and LAP in serum were not obviously raised in these patients (P >0.05).It is necessary that the value of enzymatic activities in serum for assessing the severity of brain damage and the prognosis of patients with acute head injury be further studied.