儿童后颅窝髓母细胞瘤（附42例临床分析）

Medulloblastoma of Posterior Fossa in Children Report of 42 Cases

为提高诊治水平，对４２例儿童后颅窝髓母细胞瘤的临床资料进行了分析。结果：男女之比为２∶１，平均年龄７．３岁。病变位于小脑蚓部者３６例，位于小脑半球６例。患儿均有明显颅内压增高，３９例伴重度梗阻性脑积水，３１例出现小脑功能障碍。全部病例均行手术治疗，除３例死于术后呼吸循环衰竭外其余３９例恢复良好，术后即行颅脊柱放疗及化疗。随访至今，尚无１例死亡。作者对诊断及治疗进行了讨论，强调了手术的重要性并讨论了手术技巧及术后放。

Forty two cases of medulloblastoma of posterior fossa in children are presented in this paper.Of the children,28 were males and 14 females;their age ranged from 1.5 to 12(mean 7.3) years.The foci found were in vermis (36) and cerebellar hemispheres (6).All of these children presented symptoms and signs of obviously increased intracranial pressure,and 31(77%) of them had the signs of cerebellar functional deficits.CT scan showed severe obstructive hydrocephalus in 39 cases.42 children with posterior fossa medulloblastoma underwent surgical resection.Three died of postoperative prespiratory and circulatory failure.39 made good recovery and received craniospinal radiotherapy and adjunct chemotherapy.Up to now,none died.Surgical intervention and operative procedures were emphasized particularly.Radiotherapy and chemotherapy were discussed also.