BCR-ABL阳性的儿童急性淋巴细胞白血病的研究进展
被引量:2
摘要
BCR—ABL融合基因阳性是儿童急性淋巴细胞白血病预后不良的独立危险因素。近年来,对其分子生物学基础、临床特点、检测方法、治疗和预后等方面的研究取得了一些进展。本文就此作一综述。
出处
《国际输血及血液学杂志》
CAS
2006年第6期509-512,共4页
International Journal of Blood Transfusion and Hematology
参考文献18
-
1Carroll WL, Bhojwani D, Min DJ, et al. Pediatric acute lymphoblastic leukemia. Hematology (Am Soc Hematol Educ Program) ,2003,102-131.
-
2Mundhada S, Luthra R, Cano P. Association of HLA Class Ⅰ and Class Ⅱ genes with bcr abl transcripts in leukemia patients with t(9,22) (q34;q11).BMC Cancer,2004,4:25.
-
3Telegeev GD, Dubrovska AN, Dybkov' MV, et al. Influence of BCR/ABL fusion proteins on the course of Ph leukemias. Acta Biochim Pol,2004,51(3) :845-849.
-
4Laurent E, Talpaz M, Kantarjian H, et al. The BCR gene and philadelphia chromosome-positive leukemogenesis. Cancer Res,2001,61(6):2343-2355.
-
5Kurzrock R, Kantariian HM, Druker BJ, et al. Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics. Ann Intern Med, 2003,138(10):819-830.
-
6Faderl S, Garcia-Manero G, Thomas DA, et al. Philadelphia chromosome-positive acute lymphoblastic leukemia currentconcepts and future perspectives. Rev Clin Exp Hematol, 2002, 6(2):142-160.
-
7Arico M, Valsecchi MG, Camitta B, et al. Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia. N Engl J Med,2000,342(14):998-1006.
-
8Nashed AL, Rao KW, Gulley ML. Clinical applications of BCRABL molecular testing in acute leukemia. J Mol Diagn,2003,5(2):63-72.
-
9Talano JM, Casper JT, Camitta BM, et al. Alternative donor bone marrow transplant for children with Philadelphia chromosome ALL. Bone Marrow Transplant,2006,37(2) : 135-141.
-
10Sharathkumar A, Saunders EF, Dror Y, et al. Allogeneic bone marrow transplantation vs chemotherapy for children with Philadelphia chromosome-positive acute lymphoblastic leukemia.Bone Marrow Transplant ,2004,33( 1 ) : 39-45.
同被引文献9
-
1李国霞,王慧萍,周永安,朱镭,夏丽,周岩.80例儿童急性淋巴细胞白血病的染色体分析[J].中国优生与遗传杂志,2007,15(2):42-42. 被引量:2
-
2ISCN. An intemational system for human an cytogenetic nom enclature Harndern DG, KJliger Hp, eds, Published in collaboration with cytosent cell Gene[M].Barger, 1985.
-
3Hunger SP. Chromosornal translocations involving the E2A geneinacute lymphoblastic leukemia clinical features and molecular pathogenesis[J]. Blood, 1996,87 .- 1211 - 1224.
-
4Stams WA, Beverloo HB, Den Boer ML, et al. Incidence of additional genetic changes in the TEL and AML1 gens in DCOG and COALL-treated t (12 ;21 ) -positive pediatric ALL, and their relation with drug sensitivity and clinical outcome[J].Leukemra, 2006,20 (3) :410-416.
-
5高超,李志刚,赵玮,吴敏媛.儿童急性淋巴细胞白血病e2a-pbx1融合基因的表达水平与临床特点、早期治疗反应的相关性[J].中国实验血液学杂志,2008,16(3):569-573. 被引量:12
-
6薛永权.急性淋巴细胞白血病染色体改变及其意义[J].诊断学理论与实践,2011,10(3):290-292. 被引量:7
-
7赵鼎,刘帅,郭振欣,李瑞.八探针荧光原位杂交联合R显带技术诊断儿童急性淋巴细胞白血病[J].中华医学遗传学杂志,2016,33(1):9-12. 被引量:11
-
8王青霞,刘征燕,马琳,安会波.38例儿童急性淋巴细胞白血病染色体结果分析[J].中国优生与遗传杂志,2016,24(5):64-64. 被引量:2
-
9王焕萍,徐欢,陈志姝,楼基余,金洁.荧光原位杂交技术检测105例慢性淋巴细胞白血病的分子遗传学异常[J].中华医学遗传学杂志,2017,34(3):357-360. 被引量:4
-
1马广渊,卢常青,黄婷.初诊无脾大的慢性粒细胞白血病一例[J].医学临床研究,2014,31(8).
-
2刘梦涵,罗建民.MiRNA在慢性粒细胞白血病中的研究进展[J].临床荟萃,2015,30(8):951-955.
-
3王玲玲,姜扬文.干扰素治疗慢性髓细胞白血病的研究进展[J].国际输血及血液学杂志,2014,37(2):151-154. 被引量:3
-
4潘杰,覃艳红,赵俊霞,陈秀花,徐智芳,许晶,常建梅,薛凤,张娜,任方刚,张耀方,王晓娟,王宏伟.慢性髓性白血病一种新剪接体ABL^△exon7+35INS[J].中华血液学杂志,2016,37(6):503-506. 被引量:1
-
5刘小军,罗建民,杨林,武学文,温树鹏.甲磺酸伊马替尼对K562细胞bcr/abl、SHIP-2基因表达的影响及意义[J].河北医药,2010,32(7):771-773.
-
6李珍,房佰俊.慢性粒细胞白血病的治疗进展[J].临床荟萃,2014,29(10):1126-1130. 被引量:4
-
7宋建新,朱红艳,沙玲.慢性粒细胞白血病患者血清IL-21水平检测的临床意义[J].国际检验医学杂志,2013,34(16):2103-2104. 被引量:2
-
8鲍协炳,仇惠英,陈苏宁,马骁,唐晓文,傅琤琤,孙爱宁,吴德沛.伊马替尼治疗早期BCR-ABL转录本水平在251例慢性髓性白血病患者中的预后价值[J].中华血液学杂志,2015,36(7):553-558. 被引量:7
-
9程辉,黄崇媚,邱慧颖,胡晓霞,陈莉,唐古生,章卫平,宋献民,王健民,杨建民.bcr-abl阳性急性淋巴细胞白血病分子生物学特点及预后分析[J].白血病.淋巴瘤,2015,24(12):710-714.
-
10王娟,宋永平.高三尖杉酯碱在慢性髓性白血病治疗中的作用机制[J].中华临床医师杂志(电子版),2016,10(17):2653-2656. 被引量:1