补肾定眩汤治疗椎-基底动脉供血不足的临床研究

Effect and pathogenesis of Bushendingxuantang for Vertebrobasilar Insufficiency

目的总结中药复方补肾定眩汤对椎-基底动脉供血不足(VBI)的治疗作用。方法将120例病人随机分为两组,治疗组60例,服用补肾定眩汤;对照组60例,服用盐酸氟桂利嗪(西比灵)。治疗6周,观察治疗前后病人的症状、体征,经颅多普勒(TCD)监测各项指标结果。结果治疗后两组症状疗效比较及TCD各项指标的改善有明显差异,且治疗组优于对照组(P<0.05)。结论补肾定眩汤治疗VBI疗效显著。

Objective To study the effect and pathogenesis of Bushending xuantang for vertebrobasilar insufficiency （VBI）. Methods One hundred and twenty patients （pts） with VBI were divided into two groups randomly： Test group （60 pts） and control group （60 pts）. Blood flow rate were measured and the levels were compared pre- and post- treatment. Results Following the treatment the symptoms and blood flow rate were greatly improved. The effective rate in the treatment group was higher than that in the control group （P 〈 0.05）. Conclusion Bushendingxuantang was effective for VBI.