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脂联素在冠心病发生发展中的作用

The Function of Adiponectin in the Initiation and Progression of Coronary Heart Disease
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摘要 脂联素(adiponectin)是新近发现的脂肪细胞分泌的特异性蛋白质,循环血液中含量较丰富。脂联素通过抗炎和抗动脉粥样硬化在冠心病的发生和发展中起保护作用,在控制冠心病的危险因素如肥胖、2型糖尿病及胰岛素抵抗中也起到重要作用。它为降低冠心病发病率和病死率提供一个新的思路。 Adiponectin is a newly detected specific protein secreted by adipocyte, which is abounded in blood. Adiponectin has protective actions in the initiation and progression of Coronary Heart Disease（CHD） through anti-inflammatory and anti-atberogenic effects, which also plays a crucial role in controlling CHD risk factor such as obesity, type 2 diabetes, and insulin resistance. Adiponectin will provide a new pathways to reduce the morbidity and mortality of CHD.
作者 梁允兰 彭宇竹 郭锡熔
机构地区 南京中医药大学 南京市妇幼保健院 南京医科大学儿科研究所
出处 《医学综述》 2006年第21期1300-1302,共3页 Medical Recapitulate
关键词 脂联素 冠心病 Adiponectin Coronary heart disease
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献20

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二级参考文献23

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医学综述
2006年 第21期

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