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开普拓联合放射对人宫颈癌BALB/c裸鼠移植瘤生物效应的实验研究

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摘要 宫颈癌是最常见的妇科恶性肿瘤,实行以手术和放疗为主的综合治疗,以顺铂为基础的同步放化疗化疗使宫颈癌死亡危险度下降30%-5%。开普拓(CPT-11)是一种新型的半合成的水溶性喜树碱衍生物,对转移性结肠癌、卵巢癌、小细胞肺癌、宫颈癌有较好的临床疗效心,但对CPT—11联合放射的研究很少。笔者实验利用人宫颈癌BALB/c裸鼠移植瘤为研究对象,观察CPT—11联合放射对宫颈癌的影响,为临床上CPT—11应用于放疗提供参考。
出处 《中华放射肿瘤学杂志》 CSCD 北大核心 2006年第6期451-452,共2页 Chinese Journal of Radiation Oncology
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