吸烟、饮酒与蒙古族高血压的关联性

Correlation between alcohol intake and smoking and hypertension in Mongolian people

目的探讨吸烟、饮酒与蒙古族高血压的关联及关联强度。方法对2 589名≥20岁的蒙古族居民进行血压的测量及吸烟、饮酒等因素的调查,采取单因素χ2及多因素非条件Logistic回归模型分析,以OR值作为评价关联及关联强度的指标,用Mantel-Haenszelχ2趋势检验法分析饮酒与高血压间的剂量-反应关系。结果单因素分析结果显示,年龄、性别(男性)、吸烟、饮酒、超重[体质指数(BMI)≥25]、腹型肥胖[腰臀比(WHR)≥0.9]、高血糖(血糖≥6.1)以及高血压家族史与高血压相关联(P<0.05)。经Logistic回归模型分析,调整了年龄、性别、BMI、WHR、血糖和家族史等因素后,吸烟与高血压的关联差异无统计学意义(OR=0.823,P>0.05),而饮酒与高血压之间的关联差异有统计学意义(OR=1.705,P<0.0001)。剂量-反应关系分析结果显示,蒙古族人群患高血压的危险性有随着饮酒量的增加而增高的趋势。结论饮酒可能是蒙古族高血压的独立危险因素,随着饮酒量的增加患高血压的危险性增高,而吸烟可能不是蒙古族高血压的危险因素。

Objective To investigate correlation between smoking cigarette and alcohol intake and hypertension in Mongolian people. Methods The blood pressure . etc were measured and factors including smoking cigarette and alcohol intake were investigated for 2 589 Mongolian people aged 20 and above 20 years old, the statistic analysis were done by using chi square test and multiple logistic model, and correlation and correlation intensity were evaluated by using OR, dose - effects relations between alcohol intake and hypertension were analyzed by means of Mantel - Haenszel chi square trend test. Results Results of single factor analysis showed that age, gender（male）, smoking cigarette, alcohol intake, overweight（BMI≥25）, abdomen fat （WHR≥ 0.9）, hyperglycosemia and family history of hypertension were all correlated with hypertension（ P 〈 0.05）.Alter adjustment for age, gender, BMI, WHR, blood glucose and family history of hypertension by multiple logistic model, there were no correlation between smoking cigarette and hypertension（ OR = 0. 823, P 〉 0.05 ）, there were significant correlation between alcohol intake and hypertension（ OR = 1. 705, P 〈 0. 0001 ）. Results of dose - effect analysis showed that the risk of hypertension increased with quantity of alcohol intake. Conclusion Alcohol intake could be a independent risk factor of hypertension in Mongolian people, and the risk of hypertension increased with the quantity of alcohol intake. Smoking cigarette could not be a risk factor of hypertension.