离子阱质谱计的研究现状及其进展

Introduction to Ion Trap Mass Spectrometer

离子阱质量分析器中离子的运动在数学上可用二阶线性微分方程——Mathieu方程的解来描述,利用离子在Mathieu方程解的稳定性图中所具有的特性,可实现离子的质谱扫描。离子阱质谱计的小型化主要集中在对离子阱质谱计各组成部分(离子源、质量分析器、离子检测、真空系统)的小型化上。随着科技的不断发展,离子阱质谱计体积的小型化,分析对象的不断扩大,仪器性能上实现大质量范围、高分辨率和高灵敏度,以及成本的有效降低等,将是离子阱质谱计相关研究的主要趋势。

Recently, increasing interest in mass spectrometry is focused on miniature instrumentation, especially on the development of miniature ion trap mass spectrometer. The motion of the ions can be expressed by Mathieu Equation and its stability diagram. The mass spectrum of the analyzed ions can be achieved by scanning the amplitude of the RF voltage. The miniaturization of the ion trap mass spectrometer mainly focuses on the miniaturization of components, including ion fountain, mass analyzer, ion detector and vacuum system. With the development of science and technology, the main studies focus on miniaturization, wider applications, higher resolution and wider mass range, rapid analyzing and lower cost.