款冬花的化学成分及药理活性研究进展

Phytochemical and pharmacological research progress in Tussilago farfara.

款冬花含有萜类、黄酮、生物碱等化学成分,具有止咳、祛痰、平喘的作用,以及升压作用,抗血小板活化因子作用,抗炎作用等药理活性。作者阐述了款冬花的化学成分和药理活性研究的最新进展,并针对其毒性提出了安全评价问题,指出了款冬花研究存在的主要问题和今后研究的主要方向。

Tussilagofarfara contained the chemical constitutents including terpenes, flavonoids,and alkanoids. It has been used for the relief of coughs and as an expectorant, blood pressure raiser, platelet activating factor inhibitor and anti-inflammatory agents. This paper reviewed the phytochemical and pharmacological research progress in T. farfara, including the chemical ingredients, the pharmaceutical activities and the security evaluation aiming at its toxicity. The problems at present and the reseach direction for the future on T. farfara have been put forward.