摘要
采取两种不同的方法,即分别以氨基乙酸和二溴二苯并-18-冠-6(摩尔比为2∶1)或者以氯乙酸和二氨基二苯并-18-冠-6(摩尔比为2∶1)为原料,在回流温度下,合成氨基乙酸衍生二苯并-18-冠-6,其中用二氨基二苯并-18-冠-6和氯乙酸作用下,回流7 h产率较高,可达80%。目标化合物由红外、核磁共振及元素分析等手段进行表征。
Glycine derivative of dibenzo-18-crown-6 was synthesized in two different ways. One used dibromo-dibenzo- 18-crown-6 and amino acetic acid as raw materials; and the other used 4,4＇-diamino-dibenzo-18-crown-6 and l-chloro acetic acid as raw materials under refluxed conditions. The second method was better. Under optimum conditions, the product yield was neatly 80%. The product was characterized by IR, ^1H NMR and elemental analysis.
出处
《化学世界》
CAS
CSCD
北大核心
2006年第11期682-685,共4页
Chemical World
基金
安徽省高校青年教师科研资助项目(2005jq1161)
