期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

哺乳动物上皮细胞抗菌肽分离纯化技术研究进展 被引量：2

Progress on Isolation and Purification of Epithelial Antibacterial Peptides in Mammals
下载PDF
导出
摘要 抗菌肽是在动植物体内发现的氨基酸数目少于100个的一类多肽,是哺乳动物防御体系的一个重要组成部分,具有分子质量小、对热稳定、水溶性好、广谱抗菌和作用机制独特等特点。文章主要综述了几种哺乳动物上皮细胞抗菌肽的分离纯化技术研究概况。 Antibacterial peptides are polypeptides of fewer than 100 amino acids that are found in animals and plants and they are key components of mammalian defense system. These active polypeptides have characteristics of small molecular mass,good thermo-stability,broad-speetra antibacterial activity and particu/ar antibacterial mechanism. This review summarized the present knowledge about epithelial antibacterial peptides isolated and purified in mammals.
作者 陈琛 王新华 薄新文 王运宏
机构地区 石河子大学动物科技学院 新疆生产建设兵团农垦科学院绵羊繁育生物技术重点实验室
出处 《动物医学进展》 CSCD 2006年第11期29-33,共5页 Progress In Veterinary Medicine
基金 兵团科技局基础研究项目(2006JC01)
关键词 上皮细胞抗菌肽 分离纯化 层析 哺乳动物 epithelial antibacterial peptides isolation and purification chromatography mammals
分类号 S852.2 [农业科学—基础兽医学]
  • 相关文献

参考文献21

  • 1Hase K,Ohno H.Epithelial cells as sentinels in mucosal immune barrier[J].Nihon Rinsho Meneki Gakkai Kaishi,2006,29(1):16-26.
  • 2司利钢,刘玺诚.上皮细胞抗菌肽的研究进展与儿科疾病[J].国外医学（儿科学分册）,2005,32(2):80-82. 被引量：1
  • 3Hiemstra P S.Defensins and cathelicidins in inflammatory lung disease:beyond antimicrobial activity[J].Biochem Soc Trans,2006,34:276-278.
  • 4Kamysz W.Are antimicrobial peptides an alternative for conventional antibiotics[J].Nucl Med Rev Cent East Eur,2005,8(1):78-86.
  • 5Rainard P,Riollet C.Innate immunity of the bovine mammary gland[J].Vet Res,2006,37(3):369-400.
  • 6Dziarski R,Gupta D.Mammalian PGRPs:novel antibacterial proteins[J].Cell Microbiol,2006,8(7):1059-1069.
  • 7Diamond G,Zasloff M,Eck H,et al.Tracheal antimicrobial peptide,a cysteine-rich peptide from mammalian tracheal mucosa:peptide isolation and cloning of a cDNA[J].Proc Nati Acad Sci USA,1991,88(9):3952-3956.
  • 8Tarver A P,Clark D P,Diamond G,et al.Enteric beta-defensin:molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection[J].Infect Immun,1998,66(3):1045-1056.
  • 9Aono S,Li C,Zhang G,et al.Molecular and functional characterization of bovine beta-defensin-1[J].Vet Immunol Immunopathol,2006,113(1-2):181-190.
  • 10Tydell C C,Yuan J,Tran P,et al.Bovine peptidoglycan recognition protein-S:antimicrobial activity,localization,secretion,and binding properties[J].J Immunol,2006,176(2):1154-1162.

二级参考文献44

  • 1[1]Robert E W. Hancock cationic peptide: effectors in innate immunity and novel antimicrobials. The Lancet Infectious Disease, 2001;1 :156-164
  • 2[3]Koczulla A R, Bals R. Antimicrobial peptides: current status and therapeutic potential. Drugs, 2003;63(4) :389-460
  • 3[5]Sambrook J,Frisch E F,Maniatis T.分子克隆实验指南,第二版.北京:科学出版社,1992:880-887
  • 4[6]Yan L, Adams M E. Lycotoxin, antimicrobial pepetides from venom of the wolf spider, Lycosa carolinensis. J Bio Chem, 1998; 23: 2059-2066
  • 5[7]Boman H G. Antibacterial peptides: key components needed in immunity. Cell, 1991;65 :205- 207
  • 6Wehkamp J,Harder J,Weichenthal M,et al.Inducible and constitutive β-defensins are differentially expressed in Crohn's disease and ulcerative colitis[J].Inflamm Bowel Dis,2003,9(4):215-223.
  • 7Milner SM,Cole A,Ortega MR,et al.Inducibility of HBD-2 in acute burns and chronic conditions of the lung[J].Burns,2003,29(6):553-555.
  • 8O'neil DA.Regulation of expression of β-defensins:endogenous enteric peptide antibiotics[J].Mol Immunol,2003,40(7):445-450.
  • 9Niyonsaba F,Someya A,Hirata M,et al.Evaluation of the effects of peptide antibiotics human β-defensins-1/-2 and LL-37 on histamine release and prostaglandin D2 production from mast cells[J].Eur J Immunol,2001,31(4):1066-1075.
  • 10Yang D,Biragyn A,Kwak LW,et al.Mammalian defensins in immunity:more than just microbicidial[J].Trends Immunol,2002,23(6):291-295.

共引文献37

同被引文献39

引证文献2

二级引证文献13

动物医学进展
2006年 第11期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部