36例原发性三叉神经痛患者的TSEP初步探讨

Preliminary study on TSEP in patients with primary trigeminal neuralgia.

对３６例经严格筛选的原发性三叉神经痛患者行三叉神经体感诱发电位（ＴＳＥＰ）测定，以Ｎ_（１９）作为观察指标，对其中异常者行显微血管减压术后复查。结果显示：３６例患者中，６例异常，主要有潜伏期延长和波形改变。异常者手术前后Ｎ_（１９）潜伏期差异显著，支持微血管压迫学说。但ＴＳＥＰ异常率较低，且患者组Ｎ_（１９）潜伏期与对照组无显著差异，提示ＴＳＥＰ不能作为全面评定三叉神经功能状态的灵敏指标。

Trigeminal somatcoensory evoked potential (TSEP) in 36 patients with primary trigeminal neuralgia was determined, the N_(19) wave was regarded as the observation index, and those who had an abnormal N _(19) wave were reexamined after decompression of micrangium. The result showed that abnormal N_(19)was found in 6 cases with a prolongation of the latency and a change in wave form, and there was a signifcant difference of the latency before and after operation. This condition supported the microvascular compression hypothesis. However,the abnormality rate of TSEP was low, and there was no significant difference in the latency between the diseased and the control groups,suggesting that TSEP could not be a sensitive index in the evaluation of the status of the trigeminal nerve.