豆田除草剂虎威的合成技术

Synthesis of Soybean Herbicide Fomesafen

以间羟摹苯甲酸和3，4-二氯三氟甲苯为起始原料，经过醚化、硝化和酰化3步反应合成虎威，总收率79．04％，产品纯度91．4％，研究了虎威的合成工艺，试验表明，当温度为75-80℃，反应时间为3．5～4．5h，摩尔配比为三氟羧草醚：甲基磺酰胺：三氯氧磷；1：1．03：1．62，该产品的收率可达91．7％。对合成的氟磺胺草醚经过精制处理，纯度为98．5％，各批次的质量和收率都较稳定，因此该生产工艺可以降低成本，适于工业化生产。

Applied m-hydroxybenzoic 3, 4-dichloride-trifluoride-methylbenzene as starting reagents, fomesafen was synthesized by condensation, nitration and acylation. The total yield was 79.04 % and the purity was 91.4%. The optimum process conditions were as follows： temperature 75-80℃, reaction time 3.5 -4.5 h, molar ratio of acifluorfen： methylsulfoamide： richloridephosphorusoxid = 1 ： 1.03 ： 1.62, the product yield was 91.7%. After the purification of treatment, the purity of fomesafer was 98.5%.