唾液酸测定与肺癌诊断相关性的研究

Study on the Relationship between Determination of Serum Slalic Acid and Clinical Diagnosis of Lung Cancer

应用酶法测定药盒对５４例胸部肿瘤患者进行了血清唾液酸（ＳＡ）测定，以探讨ＳＡ对肺癌的诊断价值。结果提示：肺癌患者ＳＡ水平显著增高（Ｐ＜０．０５），但无特异性。ＳＡ结合其他辅助检查，对肺癌的诊断及疗效观察有一定实用价值；也可用于肺癌高发人群的普查，以及良性和恶性肿癌的鉴别。

To evaluate serum lipid-bound sialic acid (LSA) in clinical diagnosis of lung cancer, LSA concentration was determinded by enzymatic method in 54 patients with chest tumors. The results showed that LSA of the lung cancer group was significantly higher than that of the control group (P<0.05), but it was not specific. The authors consider that LSA assay is applicable for diagnosing lung cancer and to evaluate the effect of treatment, but it must be combine with other laboratory examinations. LSA assay may bean aid to the defferential diagnosis of lung cancer from non-malignant diseases of lung and used as massive screenings of lung cancer in the high rish population.