头孢菌素类药物皮肤过敏试验探讨

On Intradermal Sensitivity Test of Cephalosporins

目的探讨有关头孢菌素皮试的问题,为临床提供参考。方法查阅相关文献,对头孢菌素皮试液浓度及其过敏反应的机制进行探讨。结果提出头孢菌素类药物的皮试液配制和皮试方法以及判断标准。结论在使用头孢菌素类药物前用拟用药物本身进行皮试,可防止药物过敏反应,确保其使用的安全性。

OBJECTIVE：To discuss the intradermal test of cephalosporlns and to provide pharmaceutical scrviees for clinicians.METHODS： Literature regarding the concentration of intradermal test solution of cephalosporins and the anaphylactic mechanism were reviewed.RESULTS ：The preparation of intradermal test solution of cephalosporins, the skin test method and the criteria in judgement were put forward for references of clinic. CONCLUSION ：Drug sensitivity test should be clone before administration of cephalosporins so as to prevent drug allergy and ensure the safety of drug use.