连续性树脂血浆灌流吸附治疗肝病性高胆红素血症13例报道

Continuous resin plasma perfusion for hepatic hyperbilirubinemia:a report of 13 cases

目的观察树脂血浆灌流吸附治疗13例肝病性高胆红素血症患者的疗效。方法13例肝病性高胆红素血症患者穴TBiL≥171μmol/L雪,采用连续性HB-H-6树脂血浆灌流吸附治疗。观察胆红素变化情况及对血压、心率、呼吸和体温的影响。结果灌流前与灌流后相比,血浆总胆红素下降53%,直接胆红素下降49%,间接胆红素下降66%;血压、心率、呼吸和体温没有明显变化。结论树脂血浆灌流吸附治疗肝病性高胆红素血症是一种安全有效的方法。

Objective To observe the clinical efficacy of resin plasma perfusion adsorption in the treatment of 13 patients with hepatic hyperbilirubinemia. Methods Thirteen patients with hepatic hyperbilirubinemia （TBiL ≥ 171 μmol/L） were treated with continuous HB-H-6 resin perfusion adsorption. Bilirubin,blood pressure,heart rate,respiration and temperture were observed. Results Compared to before perfusion,total bilirubin （TBiL） decreased 53 % ,director bilirubin （DBiL） decreased 49 %, indirector bilirubin（IBiL） decreased 66 %. There were no changes of blood pressure, heart rate, respiration and temperture. Conclusion It is demonstrated that resin plasma perfusion adsorption is an effective and safe approach in the treatment of hepatic hyperbilirubinemia.