老人院内痴呆患病率及其主要原因的研究（附临床与病理对照资料）

A investigation of the incidence and main causes of dementia in a nursing home (added the, report of a comparative study of clinic and patholoy)

对某老人院内３７６例老年人进行了痴呆患病率和痴呆病因调查，并在此基础上对其中１５例死亡患者进行了病理和临床对照研究。主要结果：（１）临床痴呆调查发现，３７６例中，痴呆及可疑痴呆者１２０例，占调查总数３１．９％；其中ＨＤＳ在１０分以下的肯定痴呆患者４４例，占调查总数１１．７％，占ＨＤＳ异常得分者总数３６．７％。不同年龄及文化背景各组中ＨＤＳ异常者的比率无显著异差．（２）对４４例肯定痴呆患者进行临床诊断分类，结果显示痴呆患者中可能为ＳＤＡＴ者２７例（６０％）；ＭＩＤ者８例（１７．５％）；ＭＩＸ者９例（２２．５％），ＳＤＡＴ比例大于ＭＩＤ和ＭＩＸ，Ｐ＜０．０１．（３）１５例脑病理检查结果表明，７例临床检查有痴呆症状的患者中，４例经病理组织学证实为ＳＤＡＴ，３例符合ＭＩＤ诊断．８例临床智力正常者，无１例发现ＳＤＡＴ改变．上述结果表明ＳＤＡＴ在我国老年人中的发病率可能高于ＭＩＤ．

Abstract It was investigated that the incidence and causes of dementia in 376 aged cases who live in a nursing home,which is a welfare service spicily for the aged, in Guangzhou. In the 376 cares, 15cases, who died of different causes, with or without dementia were studied by postmortem. The main finding as follows: (1 )In clinic, 120 cases out of 376 were dementia or probable dementia(31. 9% ) ; 44cases of whom were definite dementia, their average Hasagawa's Dementia Scale (HDS)score was less than 10 (11. 7% ). The radio of abnormal HDS was same in different age and cultural background People. (2)In the 44 cases who were definite dementia, the patients of probable SDAT were 27 (60% ) ; multiple infarct dementia (MID ) 8 (17. 5% ) and mixed dementia (MIX ) 9 (22. 5% ), the number of probable SDAT patients was much more than MID and MIX, P<0.01. (3)15 cases out of 376 were autopsied. The neuropathological results indicated that in the 7 cases suffered from dementia, 4 cases met the criteria for SDAT, and 3for MIDi but in the 8 cases of umdementia clinically,the pathological changes for SDAT were not be found.These results suggested that in China, the incidence of SDAT would be more than MID.