病人自控硬膜外镇痛泵治疗难治性腰椎间盘突出症临床观察

Clinical observation of treating refractory lumbar intervertebral disc protrusion with patient-controlled epidural analgesia(PCEA)pump

目的观察病人自控硬膜外镇痛(PCEA)泵治疗难治性腰椎间盘突出症的临床疗效。方法采用临床随机对照的方法,观察组和对照组分别应用病人自控硬膜外镇痛(PCEA)泵和用传统硬膜外注射术进行治疗,并对治疗结果进行统计分析。结果观察组痊愈31例(治愈率68.89%),好转11例(有效率93.33%),对照组痊愈18例(治愈率43.90%),好转16例(有效率82.93%)。两组治愈率比较P=0.019<0.05,差异有显著性意义,有效率比较P=0.243>0.05,差异无显著性意义。结论病人自控硬膜外镇痛(PCEA)泵治疗难治性腰椎间盘突出症治愈率要高于传统硬膜外注射术,在药物效应的基础上起液体剥离和持续给药的效果是其可能的作用机制。

Objective To observe clinical curative effect of treating refractory lumbar intervertebral disc protrusion with patlent-controlled epidural analgesia （PCEA）pump. Methods In this random and comparative trail,patlents in the observed group and the control group received patientcontrolled epidural analgesia pump and traditional epidural injection respectively. We carried out the statistical analysis to the therapeutic results. Results There were 31 patients who were cured （cute rate：68.89%）,and llpatients improved （effective rate：93.33%）in the observed group. There were 18 patients who were cured （cute rate：43.90%）,and 16 patients improved （effective rate： 82.93%）in the observed group. There were significant differences of cure rates between two groups （P=0.019〈0.05）. There are no significant difference of effective rate between two groups （P=0.243〉 0.05）. Conclusion Patient-controlled epidural analgesia （PCEA）pump is more effective than tradition epidural injection for treating patients with lumbar intervertebral disc protrusion. The possible mechanism is liquid decohesion and continue medication on the basis of therapeutic effect.