摘要
合成了阿司匹林分子印迹聚合物作为固相萃取填料,并对分子印迹固相萃取中样品溶剂、洗脱溶剂、洗脱次数及真空进样压力进行了优化选择.以丙酮为载样及清洗溶剂,乙醇为洗脱溶剂,进样压力为1200 Pa,对阿司匹林药片中的阿司匹林分子进行固相萃取,洗脱液采用紫外光度进行测定,测得含量为7.12%.测定精密度RSD为4.0%,回收率为107.3%.
The aspirin molecularly imprinted polymer had been synthesized as filling material of solid-phase extraction. The sample solvent, elution solvent, elution times and vacuum pressure of sampling were optimized for molecularly impinted solid- phase extraction （MI-SPE）. Acetone was used as a sample and cleaning solvent, ethanol as a washing solvent, and the sampling pressure was 1200 Pa. The aspirin tablet was extracted with moleculaxly imprinted solid- phase extraction and eluting solution was determined with ultraviolet spectrum. The content of aspirin was 7.12%. Relative standard deviation of aspirin determination was 4.0% and mean recovery was 115.2%.
出处
《华南师范大学学报（自然科学版）》
CAS
2006年第4期88-92,共5页
Journal of South China Normal University(Natural Science Edition)
关键词
分子印迹
固相萃取
阿司匹林
紫外光度法
molecularly imprinted
solid - phase extraction
aspirin
ultraviolet spectrum
