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黑斑息肉综合征一例报告

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出处 《医学临床研究》 CAS 2006年第11期1872-1872,F0003,共2页 Journal of Clinical Research
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  • 1Peutz JL.A very remarkable case of familial polyposis of nrucous membrane of intestinal tract and nasopharynx accompanied by peculiar pigmentations of skin and mucous membrane.Ned Maandschr Geneeskd 1921;10:134-146.
  • 2Jeghers H,Mckusick VA,Katz KH.Generalized intestinai polyposis and melanin spots of the oral mucosa,lips and digits.N Engl J Med 1949;241:993-1005.
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  • 4Hemminki A.Markie D,Tomlinson I,et al.A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.Nature 1998;391:184-187.
  • 5Jenne DE,Reimann H,Nezu J,et al.Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase.Nature Genetics 1998;18:38-43.
  • 6Wang ZJ,Ellis I,Zauber P,et al.Allelic imbalance at the LKB 1(STK 11)locus in tumour from patients with Peutzjeghers syndrome proves evidance for a hamartoma-(adenoma)-carcinoma sequence.J Pathol 1999;188:9-13.
  • 7Wang ZJ,Churchman M,Avizienyte E,et al.Germline mutations of the LKB 1(STK 11)gene in Peutz-Jeghers syndrome patients.J Med Genet 1999;36:365-368.

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