助动车尾气的V_(79)细胞微核试验

Micronucleus Induction in V_(79) Cells with Boost-cycle Exhaust Particulates

对5种牌号的助动车尾气颗粒提取物进行V_(79)细胞微核试验。结果表明,在中与高浓度时,各种牌号助动车排出颗粒提取物均可导致V_(79)细胞微核率的显著升高,且有一定的剂量—反应关系,提示其颗粒提取物具有染色体损伤作用。在中、高浓度时,永久车型微核率显著高于其他车型(中浓度时除菲利浦外),其余各牌号车型之间未发现微核率有显著差异。

Mutagenicity of the exhaust particulates of 5 domestic and imported boost-cycle has been conducted using V79 cells micronucleus test. The results showed that the extract of exhaust particulates could significantly induce micronucleus in V79 cells, and a dose-response relationship was also observed. In medium and high dose groups, frequency of micronucleated V79 cells induced by Yong Jiu Type was higher than those induced by other types (except Philips Type in meduim dose group), and no other difference in mutagenicity of exhaust particulates was found among these boost-cycles.