摘要
大鼠固定连续７天，用放免法分别测得固定前１天及固定１、３、５、７天血浆皮质酮含量。结果发现，随着固定的持续，血浆皮酮的含量逐渐升高，固定第３天即达高峰６０．４±５．０ｕｇ／ｄｌ（Ｐ〈０．０１）以后有所下降，固定第５天为５６±３．４ｕｇ／ｄｌ（Ｐ〈０．０１），第７天为４７．３±２．５ｕｇ／ｄｌ（Ｐ〈０．０１）。而对照组在相同期间皮质酮含量前后对比无显著性差异。这一结果表明，在固定应激过程中。
The wistar rats were immobilizaed for 7 days. The plasma concentration of corticosterone 1 day before immobilizing and 1?3?5?7 days after immobilization were measered respectively. The results were as followe: The concentration of plasma corticosterone increased after immobilization and reached the highest level 3 days after immobilization. The level of corticorsterone did not change significantly in control group. The results suggest that hypothalamus - pituitary-a-drenal cortex system be involed in the immobilization stress.
关键词
应激
皮质酮
血浆
生理学
corticosteron immobolization hypothalamus - pituitary - adrenal cortex system
