结节性甲状腺肿术前用碘准备对甲状腺组织学影响的临床研究

Clinic Study of Thyroid Histologically that Nodular of Goiter Which have been Prepared with Iodine and Without Iodine.

目的探讨碘过多与慢性淋巴性甲状腺炎的关系。方法将吉林大学第三临床学院1996-1998年结节性甲状腺肿及结甲合并甲亢术前用碘准备与未用碘准备各24例病人进行对比研究。结果术前用碘组及未用碘准备组显微镜下甲状腺标本淋巴细胞浸润存在显著差异，用碘准备组有16例有淋巴细胞浸润，而未用碘准备组无1例有淋巴细胞浸润。结论碘可以诱发地方性甲状腺肿和结节伴甲亢的甲状腺内淋巴细胞浸润，可能与高碘诱发自体免疫甲状腺炎相关。

Objective To study the relationship b,：tween of iodine and lymphocytic thyroiditis. Methnds Selecting clinical cases with whole materials of nodular goiter and Toxic nodular goiter which have been prepare with iodine and without iodine respectively 24 cases of before operation proceeding contrasts researches in 1996 to 1998 year. Results There were 16 cases differ degree lymphocytic infiltration prepared with iodine before operation which was significantly higher than that of the control group （0/24 P 〈 0.01）. Conclusion Excess iodine intake may induce the development of lymphocytic thyroiditis in the nodular goiter and Toxie nodular goiter. There are may correlated with between iodine excess and lymphocytic thyroiditis.