摘要
高效液相色谱技术逐渐广泛应用于代谢组学的研究中。迄今为止,该技术已经在不同生理状态的生物体液的代谢指纹谱分析中得到了应用。本文评述了传统高效液相色谱技术、毛细管技术和超高效液相色谱等技术在代谢组学的应用。
High performance liquid chromatographic（HPLC） technique has been employed in metabonomics studies recently. To date the technique has been applied to the analysis of bio-fluid obtained from studies in rodents in investigations of physiological variation and toxicity. In this review, the developments of application of conventional high performance liquid chromatography, capillary methods, ultra performance liquid chromatography are described.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2006年第11期1644-1648,共5页
Chinese Journal of Analytical Chemistry
基金
国家973计划资助项目(No.2005CB523404)
天津市科技发展计划项目(No.05YFZJC01102)
关键词
高效液相色谱
代谢组学
生物标志物
评述
High performance liquid chromatography, metabonomics, biomarker, review
