摘要
AIM： To study the effect of combined indwelling catheter, hemofiltration, respiration support and traditional Chinese medicine （e.g. Dahuang） in treating abdominal compartment syndrome of fulminant acute pancreatitis. METHODS： Patients with fulminant acute pancreatitis were divided randomly into 2 groups of combined indwelling catheter celiac drainage and intra-abdominal pressure monitoring and routine conservative measures group （group 1） and control group （group 2）. Routine non-operative conservative treatments including hemofiltration, respiration support, gastrointestinal TCM ablution were also applied in control group patients. Effectiveness of the two groups was observed, and APACHE Ⅱ scores were applied for analysis. RESULTS： On the second and fifth days after treatment, APACHE Ⅱ scores of group 1 and 2 patients were significantly different. Comparison of effectiveness （abdominalgia and burbulence relief time, hospitalization time） between groups 1 and 2 showed significant difference, as well as incidence rates of cysts formation. Mortality rates of groups 1 and 2 were 10.0% and 20.7%, respectively. For patients in group 1, celiac drainage quantity and intra-abdominal pressure, and hospitalization time were positively correlated （r = 0.552, 0.748, 0.923, P 〈 0.01） with APACHE Ⅱ scores. CONCLUSION： Combined indwelling catheter celiac drainage and intra-abdominal pressure monitoring, short veno-venous hemofiltration （SVVH）, gastrointestinal TCM ablution, respiration support have preventive and treatment effects on abdominal compartment syndrome of fulminant acute pancreatitis.
瞄准：学习联合留置导管，血过滤，呼吸支持和繁体中文药的效果(例如 Dahuang ) 在治疗暴发性的尖锐胰腺炎的腹的分隔空间症候群。方法：有暴发性的尖锐胰腺炎的病人随机被划分成监视的腹的排水和 intra 腹的压力和平淡的保守措施组(组 1 ) 和控制组织的 2 组联合留置导管(组 2 ) 。平淡的非起作用的保守疗法包括血过滤，呼吸支持，胃肠的 TCM 沐浴也在控制组病人被使用。二个组的有效性被观察，并且 APACHE II 分数被申请分析。结果：在第二和第五天术后疗法上，组 1 和 2 病人的 APACHE II 分数是显著地不同的。有效性的比较(腹痛和 burbulence 消除时间，住院时间) 在组之间， 1 和 2 显示出包囊的有效差量，以及发生率形成。组的死亡率 1 和 2 分别地是 10.0% 和 20.7% 。为在组 1 的病人，腹的排水数量和 intra 腹的压力，和住院时间断然被相关(r = 0.552， 0.748， 0.923， P<0.01 ) 与 APACHE， II 得分。结论：联合留置导管腹的排水和 intra 腹的压力监视的、短 veno 静脉的血过滤(SVVH ) ，胃肠的 TCM 沐浴，呼吸支持在暴发性的尖锐胰腺炎的腹的分隔空间症候群上有预防措施和治疗效果。
